Patrick R. O'Neil insider trades: Ionis Pharmaceuticals (IONS) stock sales
Trades on the price chart
Daily close, with an arrow on each day they bought or sold
Companies
Where Patrick reports to the SEC
Open-market buys and sales
80 trades reported on SEC Form 4, newest first
| Date | Stock | Type | Shares | Price | Value | Holding | Reported |
|---|---|---|---|---|---|---|---|
| Jun 26, 2026 | IONS | ↓ Sell10b5-1 | 3,069 | $80.00 | $246K | Direct | Jun 30, 2026 (4d) |
| Jan 30, 2026 | IONS | ↓ Sell | 6,179 | $83.53 | $516K | Direct | Feb 2, 2026 (3d) |
| Jan 16, 2026 | IONS | ↓ Sell | 9,191 | $75.84 | $697K | Direct | Jan 20, 2026 (4d) |
| Oct 6, 2025 | IONS | ↓ Sell10b5-1 | 13,441 | $69.74 | $937K | Direct | Oct 8, 2025 (2d) |
| Oct 2, 2025 | IONS | ↓ Sell10b5-1 | 64,664 | $67.69 | $4.4M | Direct | Oct 2, 2025 (0d) |
| Sep 30, 2025 | IONS | ↓ Sell10b5-1 | 25,300 | $64.62 | $1.6M | Direct | Oct 1, 2025 (1d) |
| Sep 12, 2025 | IONS | ↓ Sell10b5-1 | 1,700 | $64.58 | $110K | Direct | Sep 16, 2025 (4d) |
| Sep 9, 2025 | IONS | ↓ Sell10b5-1 | 21,000 | $64.56 | $1.4M | Direct | Sep 11, 2025 (2d) |
| Sep 3, 2025 | IONS | ↓ Sell10b5-1 | 89,900 | $60.03 | $5.4M | Direct | Sep 4, 2025 (1d) |
| Feb 20, 2025 | IONS | ↓ Sell10b5-1 | 1,207 | $32.35 | $39K | Direct | Feb 24, 2025 (4d) |
| Feb 4, 2025 | IONS | ↓ Sell10b5-1 | 6,165 | $31.62 | $195K | Direct | Feb 6, 2025 (2d) |
| Jan 31, 2025 | IONS | ↓ Sell | 1,406 | $32.49 | $46K | Direct | Feb 3, 2025 (3d) |
| Jan 16, 2025 | IONS | ↓ Sell | 7,360 | $32.83 | $242K | Direct | Jan 17, 2025 (1d) |
| Feb 2, 2024 | IONS | ↓ Sell | 1,961 | $49.67 | $97K | Direct | Feb 2, 2024 (0d) |
| Jan 25, 2024 | IONS | ↓ Sell | 6,450 | $51.75 | $334K | Direct | Jan 29, 2024 (4d) |
| Jan 17, 2024 | IONS | ↓ Sell | 7,744 | $50.42 | $390K | Direct | Jan 18, 2024 (1d) |
| Dec 26, 2023 | IONS | ↓ Sell | 20,825 | $51.46 | $1.1M | Direct | Dec 28, 2023 (2d) |
| May 24, 2023 | IONS | ↓ Sell10b5-1 | 1,527 | $41.70 | $64K | Direct | May 24, 2023 (0d) |
| Feb 6, 2023 | IONS | ↓ Sell | 1,920 | $40.86 | $78K | Direct | Feb 7, 2023 (1d) |
| Jan 31, 2023 | IONS | ↓ Sell10b5-1 | 9,000 | $39.56 | $356K | Direct | Feb 2, 2023 (2d) |
| Jan 18, 2023 | IONS | ↓ Sell | 7,836 | $39.49 | $309K | Direct | Jan 19, 2023 (1d) |
| Apr 12, 2022 | IONS | ↓ Sell10b5-1 | 6,792 | $40.06 | $272K | Direct | Apr 14, 2022 (2d) |
| Jan 25, 2021 | IONS | ↓ Sell10b5-1 | 5,324 | $63.50 | $338K | Direct | Jan 27, 2021 (2d) |
| Feb 10, 2020 | IONS | ↓ Sell10b5-1 | 3,882 | $59.60 | $231K | Direct | Feb 11, 2020 (1d) |
| Apr 5, 2019 | IONS | ↓ Sell10b5-1 | 49,528 | $83.99 | $4.2M | Direct | Apr 5, 2019 (0d) |
| Mar 18, 2019 | IONS | ↓ Sell10b5-1 | 28,800 | $78.79 | $2.3M | Direct | Mar 20, 2019 (2d) |
| Feb 27, 2019 | IONS | ↓ Sell10b5-1 | 26,800 | $68.01 | $1.8M | Direct | Mar 1, 2019 (2d) |
| Feb 12, 2019 | IONS | ↓ Sell10b5-1 | 275 | $59.50 | $16K | Direct | Feb 14, 2019 (2d) |
| Feb 5, 2019 | IONS | ↓ Sell10b5-1 | 19,600 | $59.25 | $1.2M | Direct | Feb 5, 2019 (0d) |
| Jan 3, 2019 | IONS | ↓ Sell10b5-1 | 4,400 | $54.80 | $241K | Direct | Jan 3, 2019 (0d) |
| Mar 12, 2018 | IONS | ↓ Sell10b5-1 | 1,000 | $55.00 | $55K | Direct | Mar 13, 2018 (1d) |
| Jan 29, 2018 | IONS | ↓ Sell10b5-1 | 355 | $55.00 | $20K | Direct | Jan 31, 2018 (2d) |
| Jan 25, 2018 | IONS | ↓ Sell10b5-1 | 645 | $55.00 | $35K | Direct | Jan 29, 2018 (4d) |
| Jan 16, 2018 | IONS | ↓ Sell | 2,697 | $51.76 | $140K | Direct | Jan 17, 2018 (1d) |
| Dec 1, 2017 | IONS | ↓ Sell10b5-1 | 1,000 | $55.50 | $56K | Direct | Dec 1, 2017 (0d) |
| Nov 1, 2017 | IONS | ↓ Sell10b5-1 | 1,000 | $58.35 | $58K | Direct | Nov 3, 2017 (2d) |
| Oct 5, 2017 | IONS | ↓ Sell10b5-1 | 1,000 | $55.00 | $55K | Direct | Oct 6, 2017 (1d) |
| Sep 6, 2017 | IONS | ↓ Sell10b5-1 | 1,000 | $55.00 | $55K | Direct | Sep 7, 2017 (1d) |
| Jun 1, 2017 | IONS | ↓ Sell10b5-1 | 70 | $48.00 | $3K | Direct | Jun 2, 2017 (1d) |
| May 1, 2017 | IONS | ↓ Sell10b5-1 | 650 | $48.75 | $32K | Direct | May 3, 2017 (2d) |
| Apr 24, 2017 | IONS | ↓ Sell10b5-1 | 500 | $45.00 | $23K | Direct | Apr 26, 2017 (2d) |
| Apr 12, 2017 | IONS | ↓ Sell10b5-1 | 1,000 | $40.07 | $40K | Direct | Apr 13, 2017 (1d) |
| Mar 1, 2017 | IONS | ↓ Sell10b5-1 | 1,500 | $49.29 | $74K | Direct | Mar 2, 2017 (1d) |
| Feb 6, 2017 | IONS | ↓ Sell10b5-1 | 1,500 | $46.17 | $69K | Direct | Feb 8, 2017 (2d) |
| Jan 17, 2017 | IONS | ↓ Sell | 2,246 | $46.29 | $104K | Direct | Jan 18, 2017 (1d) |
| Dec 5, 2016 | IONS | ↓ Sell10b5-1 | 350 | $45.00 | $16K | Direct | Dec 7, 2016 (2d) |
| Nov 14, 2016 | IONS | ↓ Sell10b5-1 | 1,000 | $45.00 | $45K | Direct | Nov 14, 2016 (0d) |
| Apr 6, 2016 | IONS | ↓ Sell10b5-1 | 1,000 | $45.00 | $45K | Direct | Apr 7, 2016 (1d) |
| Mar 23, 2016 | IONS | ↓ Sell10b5-1 | 1,000 | $45.40 | $45K | Direct | Mar 24, 2016 (1d) |
| Jan 19, 2016 | IONS | ↓ Sell | 1,871 | $41.46 | $78K | Direct | Jan 19, 2016 (0d) |
Each row is one filing's trades in one stock, summed. Shares and prices are as filed, before any later stock split.
Other IONS insiders
Open-market trades in the last 12 months
About Patrick R. O'Neil's insider trades
Patrick R. O'Neil is EVP CLO & General Counsel at Ionis Pharmaceuticals (IONS). Since Jan 4, 2013, Patrick has reported no open-market purchases and 80 sales worth $35.4M on SEC Form 4. In the last 12 months: 3 sales ($1.5M).
62 sales (88% of the value sold) were made under a Rule 10b5-1 trading plan, which is set up months in advance and runs on a schedule, so they say little about how the insider sees the stock today.
Their filings also include option exercises (68 filings), grants and awards (32 filings), other transactions (26 filings), shares withheld for taxes (4 filings). These aren't open-market trades and aren't counted above.
How to read insider trades
Officers, directors and owners of more than 10% of a company must report trades in its stock on SEC Form 4, usually within two business days. Purchases with their own money are the stronger signal: insiders sell for many reasons (taxes, diversification, a house), but buy for one. See every IONS insider trade, the latest insider trades across the market, or cluster buys, when several insiders buy the same stock within days.

