Joseph Klein III insider trades: Ionis Pharmaceuticals (IONS) stock buys and sales
Trades on the price chart
Daily close, with an arrow on each day they bought or sold
Companies
Where Joseph reports to the SEC






and 5 more companies
Open-market buys and sales
106 trades reported on SEC Form 4, newest first
| Date | Stock | Type | Shares | Price | Value | Holding | Reported |
|---|---|---|---|---|---|---|---|
| Jul 1, 2026 | IONS | ↓ Sell10b5-1 | 11,518 | $79.04 | $910K | Direct | Jul 6, 2026 (5d) |
| May 1, 2026 | IONS | ↓ Sell10b5-1 | 10,111 | $73.51 | $743K | Direct | May 5, 2026 (4d) |
| Apr 1, 2026 | IONS | ↓ Sell10b5-1 | 22,321 | $75.55 | $1.7M | Direct | Apr 2, 2026 (1d) |
| Mar 3, 2026 | IONS | ↓ Sell10b5-1 | 21,332 | $79.51 | $1.7M | Direct | Mar 5, 2026 (2d) |
| Nov 25, 2025 | IONS | ↓ Sell10b5-1 | 4,000 | $80.00 | $320K | by Trust | Nov 28, 2025 (3d) |
| Sep 3, 2025 | IONS | ↓ Sell10b5-1 | 28,000 | $60.00 | $1.7M | by Trust | Sep 4, 2025 (1d) |
| Sep 3, 2025 | IONS | ↓ Sell10b5-1 | 28,000 | $60.00 | $1.7M | by Trust | Sep 4, 2025 (1d) |
| Jul 16, 2024 | IONS | ↓ Sell10b5-1 | 12,000 | $50.00 | $600K | by Trust | Jul 17, 2024 (1d) |
| May 3, 2024 | IONS | ↓ Sell | 6,000 | $42.71 | $256K | by Trust | May 7, 2024 (4d) |
| Nov 15, 2023 | IONS | ↓ Sell10b5-1 | 2,000 | $50.00 | $100K | Direct | Nov 17, 2023 (2d) |
| Sep 26, 2023 | IONS | ↓ Sell10b5-1 | 2,000 | $45.13 | $90K | Direct | Sep 28, 2023 (2d) |
| Jul 18, 2023 | IONS | ↓ Sell10b5-1 | 3,555 | $42.00 | $149K | Direct | Jul 19, 2023 (1d) |
| Jan 17, 2023 | IONS | ↓ Sell10b5-1 | 2,000 | $40.00 | $80K | Direct | Jan 18, 2023 (1d) |
| Jul 15, 2022 | IONS | ↓ Sell10b5-1 | 1,333 | $38.24 | $51K | Direct | Jul 19, 2022 (4d) |
| Jul 15, 2021 | IONS | ↓ Sell10b5-1 | 4,334 | $35.30 | $153K | Direct | Jul 19, 2021 (4d) |
| Oct 20, 2020 | IONS | ↓ Sell10b5-1 | 2,889 | $46.86 | $135K | Direct | Oct 22, 2020 (2d) |
| Dec 23, 2019 | IONS | ↓ Sell10b5-1 | 1,000 | $61.87 | $62K | Direct | Dec 23, 2019 (0d) |
| Dec 16, 2019 | IONS | ↓ Sell10b5-1 | 1,000 | $65.45 | $65K | Direct | Dec 18, 2019 (2d) |
| Dec 9, 2019 | IONS | ↓ Sell10b5-1 | 1,000 | $63.74 | $64K | Direct | Dec 10, 2019 (1d) |
| Dec 2, 2019 | IONS | ↓ Sell10b5-1 | 1,000 | $64.08 | $64K | Direct | Dec 4, 2019 (2d) |
| Nov 25, 2019 | IONS | ↓ Sell10b5-1 | 812 | $62.90 | $51K | Direct | Nov 26, 2019 (1d) |
| Nov 20, 2019 | IONS | ↓ Sell10b5-1 | 2,000 | $60.00 | $120K | Direct | Nov 21, 2019 (1d) |
| Mar 29, 2018 | IONS | ↓ Sell10b5-1 | 2,000 | $46.15 | $92K | Direct | Mar 30, 2018 (1d) |
| Mar 15, 2018 | IONS | ↓ Sell10b5-1 | 2,000 | $51.13 | $102K | Direct | Mar 16, 2018 (1d) |
| Feb 28, 2018 | IONS | ↓ Sell10b5-1 | 3,000 | $51.91 | $156K | Direct | Mar 1, 2018 (1d) |
| Feb 15, 2018 | IONS | ↓ Sell10b5-1 | 3,000 | $48.99 | $147K | Direct | Feb 16, 2018 (1d) |
| Jan 16, 2018 | IONS | ↓ Sell10b5-1 | 3,000 | $52.52 | $158K | Direct | Jan 17, 2018 (1d) |
| Dec 29, 2017 | IONS | ↓ Sell10b5-1 | 3,000 | $50.56 | $152K | Direct | Jan 2, 2018 (4d) |
| Dec 15, 2017 | IONS | ↓ Sell10b5-1 | 3,000 | $51.69 | $155K | Direct | Dec 19, 2017 (4d) |
| Nov 30, 2017 | IONS | ↓ Sell10b5-1 | 3,000 | $53.55 | $161K | Direct | Dec 1, 2017 (1d) |
| Nov 15, 2017 | IONS | ↓ Sell10b5-1 | 2,250 | $53.56 | $121K | Direct | Nov 17, 2017 (2d) |
| Nov 13, 2017 | IONS | ↓ Sell10b5-1 | 3,000 | $55.39 | $166K | Direct | Nov 14, 2017 (1d) |
| Nov 11, 2015 | ISIS | ↓ Sell | 6,875 | $64.18 | $441K | Direct | Nov 12, 2015 (1d) |
| Mar 5, 2015 | ISIS | ↓ Sell | 7,000 | $70.95 | $497K | Direct | Mar 9, 2015 (4d) |
| Jan 24, 2014 | ISIS | ↓ Sell | 10,313 | $48.66 | $502K | Direct | Jan 24, 2014 (0d) |
| Nov 25, 2013 | ISIS | ↓ Sell | 6,000 | $36.86 | $221K | Direct | Nov 27, 2013 (2d) |
| Aug 9, 2013 | ISIS | ↓ Sell | 11,250 | $28.22 | $317K | Direct | Aug 13, 2013 (4d) |
| Mar 20, 2013 | ISIS | ↓ Sell10b5-1 | 27,209 | $18.00 | $490K | By Son | Mar 21, 2013 (1d) |
| Mar 20, 2013 | ISIS | ↓ Sell10b5-1 | 15,567 | $18.00 | $280K | By Daughter | Mar 21, 2013 (1d) |
| Mar 20, 2013 | ISIS | ↓ Sell10b5-1 | 3,924 | $18.00 | $71K | By Son | Mar 21, 2013 (1d) |
| Mar 13, 2013 | ISIS | ↓ Sell10b5-1 | 13,867 | $18.01 | $250K | By Son | Mar 14, 2013 (1d) |
| Mar 13, 2013 | ISIS | ↓ Sell10b5-1 | 6,933 | $18.01 | $125K | By Daughter | Mar 14, 2013 (1d) |
| Mar 8, 2010 | BMRN | ↓ Sell | 10,000 | $22.12 | $221K | Direct | Mar 10, 2010 (2d) |
| Feb 1, 2010 | OSIP | ↑ Buy | 1,000 | $34.00 | $34K | By Joseph Klein III 5% Charitable Remain | Feb 2, 2010 (1d) |
| Jan 25, 2010 | OSIP | ↑ Buy | 1,000 | $34.00 | $34K | By Joseph Klein III 5% Charitable Remain | Jan 26, 2010 (1d) |
| Jan 21, 2010 | OSIP | ↑ Buy | 1,000 | $34.00 | $34K | By Joseph Klein III 5% Charitable Remain | Jan 25, 2010 (4d) |
| Jan 11, 2010 | OSIP | ↑ Buy | 1,000 | $32.09 | $32K | By Joseph Klein III 5% Charitable Remain | Jan 12, 2010 (1d) |
| Jan 4, 2010 | OSIP | ↑ Buy | 1,000 | $31.13 | $31K | By Joseph Klein III 5% Charitable Remain | Jan 5, 2010 (1d) |
| Nov 4, 2009 | PDLI | ↓ Sell | 24,000 | $8.33 | $200K | Direct | Nov 6, 2009 (2d) |
| Mar 5, 2009 | BMRN | ↑ Buy | 5,000 | $10.07 | $50K | Direct | Mar 13, 2009 (8d) |
Each row is one filing's trades in one stock, summed. Shares and prices are as filed, before any later stock split.
Other IONS insiders
Open-market trades in the last 12 months
About Joseph Klein III's insider trades
Joseph Klein III is a director at Ionis Pharmaceuticals (IONS). Since Dec 15, 2005, Joseph has reported 47 open-market purchases worth $947K and 59 sales worth $18.7M on SEC Form 4. In the last 12 months: 5 sales ($5.4M).
36 sales (70% of the value sold) were made under a Rule 10b5-1 trading plan, which is set up months in advance and runs on a schedule, so they say little about how the insider sees the stock today.
Their filings also include grants and awards (65 filings), option exercises (43 filings), shares returned to the company (4 filings), gifts (4 filings). These aren't open-market trades and aren't counted above.
How to read insider trades
Officers, directors and owners of more than 10% of a company must report trades in its stock on SEC Form 4, usually within two business days. Purchases with their own money are the stronger signal: insiders sell for many reasons (taxes, diversification, a house), but buy for one. See every IONS insider trade, the latest insider trades across the market, or cluster buys, when several insiders buy the same stock within days.