Opaleye Management Inc. insider trades: Grace Therapeutics (GRCE) stock buys and sales
Trades on the price chart
Daily close, with an arrow on each day they bought or sold
Companies
Where Opaleye Management Inc. reports to the SEC






and 10 more companies
Open-market buys and sales
320 trades reported on SEC Form 4, newest first
| Date | Stock | Type | Shares | Price | Value | Holding | Reported |
|---|---|---|---|---|---|---|---|
| Nov 5, 2026 | GRCE | ↑ Buy | 18,442 | $1.79 | $33K | By Opaleye, L.P. | Nov 5, 2026 (0d) |
| Oct 26, 2026 | GRCE | ↑ Buy | 87,801 | $1.81 | $159K | By Opaleye, L.P. | Oct 26, 2026 (0d) |
| Oct 23, 2026 | ACOG | ↑ Buy | 32,090 | $8.28 | $266K | By Opaleye, L.P. | Oct 26, 2026 (3d) |
| Oct 19, 2026 | GRCE | ↑ Buy | 4,256 | $1.88 | $8K | By Opaleye, L.P. | Oct 21, 2026 (2d) |
| Oct 16, 2026 | ACOG | ↑ Buy | 36,940 | $8.35 | $309K | By Opaleye, L.P. | Oct 19, 2026 (3d) |
| Oct 16, 2026 | GRCE | ↑ Buy | 71,065 | $1.92 | $136K | By Opaleye, L.P. | Oct 16, 2026 (0d) |
| Oct 12, 2026 | GRCE | ↑ Buy | 14,632 | $2.03 | $30K | By Opaleye, L.P. | Oct 13, 2026 (1d) |
| Oct 5, 2026 | GRCE | ↑ Buy | 60,490 | $2.05 | $124K | By Opaleye, L.P. | Oct 5, 2026 (0d) |
| Oct 1, 2026 | ACOG | ↑ Buy | 19,050 | $8.69 | $166K | By Opaleye, L.P. | Oct 2, 2026 (1d) |
| Sep 29, 2026 | GRCE | ↑ Buy | 7,849 | $2.09 | $16K | By Opaleye, L.P. | Oct 1, 2026 (2d) |
| Sep 25, 2026 | ACOG | ↑ Buy | 31,763 | $8.53 | $271K | By Opaleye, L.P. | Sep 28, 2026 (3d) |
| Sep 23, 2026 | GRCE | ↑ Buy | 15,089 | $2.10 | $32K | By Opaleye, L.P. | Oct 1, 2026 (8d) |
| Sep 23, 2026 | GRCE | ↑ Buy | 15,089 | $2.10 | $32K | By Opaleye, L.P. | Sep 23, 2026 (0d) |
| Sep 16, 2026 | ACOG | ↑ Buy | 123,918 | $8.57 | $1.1M | By Opaleye, L.P. | Sep 16, 2026 (0d) |
| Sep 11, 2026 | SLGL | ↑ Buy | 3,124 | $66.39 | $207K | By Opaleye, L.P. | Sep 14, 2026 (3d) |
| Sep 2, 2026 | SLGL | ↑ Buy | 1,683 | $69.21 | $116K | By Opaleye, L.P. | Sep 3, 2026 (1d) |
| Aug 31, 2026 | SLGL | ↑ Buy | 40,330 | $69.19 | $2.8M | By Opaleye, L.P. | Aug 31, 2026 (0d) |
| Aug 14, 2026 | GRCE | ↑ Buy | 11,608 | $2.09 | $24K | By Opaleye, L.P. | Aug 19, 2026 (5d) |
| Aug 12, 2026 | SLGL | ↑ Buy | 951 | $71.50 | $68K | By Opaleye, L.P. | Aug 14, 2026 (2d) |
| Aug 3, 2026 | ACOG | ↑ Buy | 52,900 | $8.00 | $423K | By Opaleye, L.P. | Aug 4, 2026 (1d) |
| Jul 23, 2026 | ACOG | ↑ Buy | 190,086 | $7.82 | $1.5M | By Opaleye, L.P. | Jul 24, 2026 (1d) |
| Jul 22, 2026 | ACOG | ↑ Buy | 10,000 | $7.83 | $78K | By Managed Account | Jul 24, 2026 (2d) |
| Jul 14, 2026 | ETON | ↓ Sell | 15,000 | $37.54 | $563K | By Opaleye, L.P. | Jul 17, 2026 (3d) |
| Jul 14, 2026 | ETON | ↓ Sell | 13,315 | $37.54 | $500K | By Managed Account | Jul 17, 2026 (3d) |
| Jul 14, 2026 | ETON | ↓ Sell | 15,000 | $37.54 | $563K | By Opaleye, L.P. | Jul 16, 2026 (2d) |
| Jul 14, 2026 | ETON | ↓ Sell | 13,315 | $37.54 | $500K | By Managed Account | Jul 16, 2026 (2d) |
| Jul 14, 2026 | SLGL | ↑ Buy | 1,695 | $73.64 | $125K | By Opaleye, L.P. | Jul 15, 2026 (1d) |
| Jul 10, 2026 | SLGL | ↑ Buy | 529 | $73.80 | $39K | By Opaleye, L.P. | Jul 10, 2026 (0d) |
| Jul 7, 2026 | ETON | ↓ Sell | 95,000 | $37.66 | $3.6M | By Opaleye, L.P. | Jul 7, 2026 (0d) |
| Jul 7, 2026 | ETON | ↓ Sell | 31,685 | $37.59 | $1.2M | By Managed Account | Jul 7, 2026 (0d) |
| Jul 2, 2026 | SLGL | ↑ Buy | 1,712 | $71.97 | $123K | By Opaleye, L.P. | Jul 2, 2026 (0d) |
| Jun 26, 2026 | ACOG | ↑ Buy | 152,533 | $6.40 | $976K | By Opaleye, L.P. | Jun 29, 2026 (3d) |
| Jun 15, 2026 | ACOG | ↑ Buy | 7,685 | $5.96 | $46K | By Opaleye, L.P. | Jun 15, 2026 (0d) |
| Jun 10, 2026 | ACOG | ↑ Buy | 30,728 | $5.98 | $184K | By Opaleye, L.P. | Jun 11, 2026 (1d) |
| Jun 5, 2026 | ACOG | ↑ Buy | 10,054 | $5.83 | $59K | By Opaleye, L.P. | Jun 9, 2026 (4d) |
| May 29, 2026 | ACOG | ↑ Buy | 73,738 | $5.90 | $435K | By Opaleye, L.P. | May 29, 2026 (0d) |
| May 21, 2026 | ACOG | ↑ Buy | 24,376 | $5.77 | $141K | By Opaleye, L.P. | May 22, 2026 (1d) |
| May 20, 2026 | SLGL | ↑ Buy | 1,563 | $64.43 | $101K | By Opaleye, L.P. | May 22, 2026 (2d) |
| May 18, 2026 | ACOG | ↑ Buy | 34,043 | $5.76 | $196K | By Opaleye, L.P. | May 19, 2026 (1d) |
| May 13, 2026 | SLGL | ↑ Buy | 3,437 | $67.36 | $232K | By Opaleye, L.P. | May 14, 2026 (1d) |
| Apr 29, 2026 | SNWV | ↓ Sell | 67,148 | $18.04 | $1.2M | By Opaleye, L.P. | Apr 30, 2026 (1d) |
| Apr 29, 2026 | SNWV | ↓ Sell | 3,500 | $18.12 | $63K | By Managed account | Apr 30, 2026 (1d) |
| Apr 21, 2026 | SNWV | ↓ Sell | 11,469 | $20.46 | $235K | By Opaleye, L.P. | Apr 21, 2026 (0d) |
| Apr 17, 2026 | SNWV | ↓ Sell | 5,000 | $20.46 | $102K | By Managed account | Apr 21, 2026 (4d) |
| Mar 30, 2026 | ACOG | ↑ Buy | 11,850 | $5.06 | $60K | By Opaleye, L.P. | Mar 31, 2026 (1d) |
| Mar 24, 2026 | SLGL | ↑ Buy | 34,665 | $72.00 | $2.5M | By Opaleye, L.P. | Mar 24, 2026 (0d) |
| Mar 24, 2026 | SLGL | ↑ Buy | 5,000 | $72.00 | $360K | By Managed Account | Mar 24, 2026 (0d) |
| Mar 19, 2026 | ACOG | ↑ Buy | 4,575 | $5.73 | $26K | By Opaleye, L.P. | Mar 20, 2026 (1d) |
| Mar 16, 2026 | ACOG | ↑ Buy | 1,331 | $5.78 | $8K | By Opaleye, L.P. | Mar 18, 2026 (2d) |
| Mar 9, 2026 | ACOG | ↑ Buy | 4,079 | $5.82 | $24K | By Opaleye, L.P. | Mar 10, 2026 (1d) |
Each row is one filing's trades in one stock, summed. Shares and prices are as filed, before any later stock split.
About Opaleye Management Inc.'s insider trades
Opaleye Management Inc. is a 10% owner of Grace Therapeutics (GRCE). Since May 19, 2015, it has reported 249 open-market purchases worth $69.4M and 71 sales worth $41.2M on SEC Form 4. In the last 12 months: 60 buys ($19.1M) and 24 sales ($25.3M).
Its filings also include option exercises (1 filing), other transactions (1 filing). These aren't open-market trades and aren't counted above.
How to read insider trades
Officers, directors and owners of more than 10% of a company must report trades in its stock on SEC Form 4, usually within two business days. Purchases with their own money are the stronger signal: insiders sell for many reasons (taxes, diversification, a house), but buy for one. See every GRCE insider trade, the latest insider trades across the market, or cluster buys, when several insiders buy the same stock within days.