DP
David E I Pyott
Director

David E I Pyott insider trades: Alnylam Pharmaceuticals (ALNY) stock buys and sales

Director, Alnylam Pharmaceuticals Last trade Jun 1, 2026 152 Form 4 filings
$1.1M
Sold, last 12 months
1 sale
$0
Bought, last 12 months
0 buys
31
Open-market trades
since 2006
8
Companies
last trade 2026

Trades on the price chart

Daily close, with an arrow on each day they bought or sold

Companies

Where David reports to the SEC

and 2 more companies

Open-market buys and sales

31 trades reported on SEC Form 4, newest first

DateStockTypeValue
Jun 1, 2026ALNY↓ Sell$1.1M
Mar 24, 2025ALNY↓ Sell$2.2M
Jun 24, 2024ALNY↓ Sell$7.2M
Aug 31, 2020BMRN↑ Buy$1.0M
Feb 3, 2020AVY↓ Sell$667K
Nov 27, 2018AVY↓ Sell$186K
Aug 30, 2017AVY↓ Sell$188K
Oct 13, 2016ALNY↑ Buy$1.0M
Aug 8, 2016AVY↓ Sell$157K
Nov 2, 2015AVY↓ Sell$130K
Feb 12, 2014AGN↓ Sell$31.0M
May 1, 2013EW↑ Buy$189K
Oct 5, 2012AGN↓ Sell10b5-1$57.8M
Aug 6, 2012EW↓ Sell$684K
Jan 18, 2012EW↓ Sell$1.5M
Dec 22, 2011AGN↓ Sell10b5-1$48.8M
Dec 23, 2010AGN↓ Sell10b5-1$2.6M
Nov 19, 2010EW↓ Sell$3.2M
Nov 11, 2010EW↓ Sell$466K
Nov 5, 2010AGN↓ Sell$48.7M
Feb 18, 2010EW↓ Sell$1.4M
Nov 6, 2008AGN↑ Buy$959K
Dec 7, 2007(AGN)↓ Sell10b5-1$30.4M
Aug 8, 2007(AGN)↓ Sell10b5-1$17.4M
Aug 3, 2007(AGN)↓ Sell10b5-1$14.9M
Nov 20, 2006(AGN)↓ Sell10b5-1$7.0M
Aug 16, 2006(AGN)↓ Sell$2.0M
Aug 15, 2006(AGN)↓ Sell$2.7M
Aug 15, 2006(AGN)↓ Sell$2.2M
Aug 15, 2006(AGN)↓ Sell$1.7M
Aug 14, 2006(AGN)↓ Sell$6.6M

Each row is one filing's trades in one stock, summed. Shares and prices are as filed, before any later stock split.

Other ALNY insiders

Open-market trades in the last 12 months

About David E I Pyott's insider trades

David E I Pyott is a director at Alnylam Pharmaceuticals (ALNY). Since Aug 14, 2006, David has reported 4 open-market purchases worth $3.2M and 27 sales worth $292.9M on SEC Form 4. In the last 12 months: 1 sale ($1.1M).

7 sales (61% of the value sold) were made under a Rule 10b5-1 trading plan, which is set up months in advance and runs on a schedule, so they say little about how the insider sees the stock today.

Their filings also include grants and awards (103 filings), option exercises (41 filings), gifts (9 filings), shares withheld for taxes (7 filings). These aren't open-market trades and aren't counted above.

How to read insider trades

Officers, directors and owners of more than 10% of a company must report trades in its stock on SEC Form 4, usually within two business days. Purchases with their own money are the stronger signal: insiders sell for many reasons (taxes, diversification, a house), but buy for one. See every ALNY insider trade, the latest insider trades across the market, or cluster buys, when several insiders buy the same stock within days.