Baker Bros. Advisors (GP) LLC insider trades: Madrigal Pharmaceuticals (MDGL) stock buys and sales
Trades on the price chart
Daily close, with an arrow on each day they bought or sold
Companies
Where Baker Bros. Advisors (GP) LLC reports to the SEC






and 35 more companies
Open-market buys and sales
209 trades reported on SEC Form 4, newest first
| Date | Stock | Type | Shares | Price | Value | Holding | Reported |
|---|---|---|---|---|---|---|---|
| Nov 6, 2026 | MDGL | ↑ Buy | 91,806 | $381.49 | $35.0M | Indirect | Nov 6, 2026 (0d) |
| Nov 5, 2026 | KOD | ↑ Buy | 247,090 | $98.51 | $24.3M | Indirect | Nov 6, 2026 (1d) |
| Sep 29, 2026 | KOD | ↑ Buy | 715,592 | $88.59 | $63.4M | Indirect | Sep 30, 2026 (1d) |
| Sep 28, 2026 | KOD | ↑ Buy | 807,840 | $72.57 | $58.6M | Indirect | Sep 30, 2026 (2d) |
| Sep 28, 2026 | KOD | ↑ Buy | 418,323 | $83.58 | $35.0M | Indirect | Sep 30, 2026 (2d) |
| Jul 14, 2026 | CELC | ↓ Sell | 3,100,000 | $102.50 | $317.8M | Indirect | Jul 16, 2026 (2d) |
| May 22, 2026 | ONC | ↓ Sell | 10,998 | $23.82 | $262K | Indirect | May 27, 2026 (5d) |
| Dec 18, 2025 | KOD | ↑ Buy | 2,608,696 | $23.00 | $60.0M | Indirect | Dec 19, 2025 (1d) |
| Dec 11, 2025 | KYMR | ↑ Buy | 2,005,813 | $86.00 | $172.5M | Indirect | Dec 11, 2025 (0d) |
| Nov 20, 2025 | TRDA | ↑ Buy | 28,867 | $9.07 | $262K | Indirect | Nov 24, 2025 (4d) |
| Nov 12, 2025 | TRDA | ↑ Buy | 178,044 | $7.60 | $1.4M | Indirect | Nov 12, 2025 (0d) |
| Oct 1, 2025 | KALA | ↓ Sell | 730,408 | $1.45 | $1.1M | Indirect | Oct 2, 2025 (1d) |
| Sep 8, 2025 | CELC | ↑ Buy | 170,100 | $56.27 | $9.6M | Indirect | Sep 10, 2025 (2d) |
| Aug 20, 2025 | MDGL | ↑ Buy | 97,065 | $380.58 | $36.9M | Indirect | Aug 20, 2025 (0d) |
| Aug 18, 2025 | MDGL | ↑ Buy | 68,618 | $364.04 | $25.0M | Indirect | Aug 20, 2025 (2d) |
| Jun 30, 2025 | KYMR | ↑ Buy | 655,500 | $44.00 | $28.8M | Indirect | Jun 30, 2025 (0d) |
| Mar 17, 2025 | IMCR | ↑ Buy | 807,338 | $29.72 | $24.0M | Indirect | Mar 19, 2025 (2d) |
| Feb 28, 2025 | ONC | ↓ Sell | 732,827 | $260.00 | $190.5M | Indirect | Feb 28, 2025 (0d) |
| Dec 30, 2024 | KALA | ↑ Buy | 310,559 | $6.44 | $2.0M | Indirect | Dec 31, 2024 (1d) |
| Dec 16, 2024 | BCYC | ↑ Buy | 1,485,397 | $14.29 | $21.2M | Indirect | Dec 17, 2024 (1d) |
| Dec 9, 2024 | BGNE | ↓ Sell | 1,037,017 | $187.27 | $194.2M | Indirect | Dec 10, 2024 (1d) |
| Aug 20, 2024 | KYMR | ↑ Buy | 1 | $46.41 | $46 | Indirect | Aug 22, 2024 (2d) |
| Mar 28, 2024 | IGMS | ↑ Buy | 395,317 | $8.67 | $3.4M | Indirect | Mar 28, 2024 (0d) |
| Dec 15, 2023 | IGMS | ↑ Buy | 532,693 | $6.44 | $3.4M | Indirect | Dec 15, 2023 (0d) |
| Dec 14, 2023 | MDGL | ↑ Buy | 101,792 | $221.20 | $22.5M | Indirect | Dec 14, 2023 (0d) |
| Dec 12, 2023 | MDGL | ↑ Buy | 34,578 | $218.31 | $7.5M | Indirect | Dec 14, 2023 (2d) |
| Nov 21, 2023 | MDGL | ↑ Buy | 64,350 | $188.47 | $12.1M | Indirect | Nov 21, 2023 (0d) |
| Nov 20, 2023 | MDGL | ↑ Buy | 67,079 | $178.11 | $11.9M | Indirect | Nov 21, 2023 (1d) |
| Nov 15, 2023 | MDGL | ↑ Buy | 49,387 | $158.13 | $7.8M | Indirect | Nov 15, 2023 (0d) |
| Nov 14, 2023 | MDGL | ↑ Buy | 107,499 | $146.99 | $15.8M | Indirect | Nov 15, 2023 (1d) |
| Nov 14, 2023 | BGNE | ↓ Sell | 1,100,000 | $180.50 | $198.6M | Indirect | Nov 14, 2023 (0d) |
| Oct 19, 2023 | BCEL | ↓ Sell | 274,739 | $0.40 | $111K | Indirect | Oct 23, 2023 (4d) |
| Aug 17, 2023 | NLTX | ↑ Buy | 2,285,342 | $0.64 | $1.5M | Indirect | Aug 17, 2023 (0d) |
| May 24, 2023 | ACAD | ↑ Buy | 896,522 | $25.33 | $22.7M | Indirect | May 24, 2023 (0d) |
| Jun 6, 2022 | KOD | ↑ Buy | 572,349 | $7.77 | $4.4M | Indirect | Jun 6, 2022 (0d) |
| Jun 6, 2022 | TRDA | ↑ Buy | 40,947 | $6.37 | $261K | Indirect | Jun 6, 2022 (0d) |
| May 27, 2022 | KOD | ↑ Buy | 350,406 | $6.75 | $2.4M | Indirect | May 27, 2022 (0d) |
| May 24, 2022 | TRDA | ↑ Buy | 48,509 | $5.82 | $282K | Indirect | May 24, 2022 (0d) |
| May 18, 2022 | KOD | ↑ Buy | 456,690 | $5.91 | $2.7M | Indirect | May 18, 2022 (0d) |
| May 18, 2022 | TRDA | ↑ Buy | 71,944 | $5.99 | $431K | Indirect | May 18, 2022 (0d) |
| May 11, 2022 | TCRX | ↑ Buy | 1,359,792 | $1.88 | $2.6M | Indirect | May 12, 2022 (1d) |
| Mar 10, 2022 | INCY | ↑ Buy | 389,080 | $72.24 | $28.1M | Indirect | Mar 10, 2022 (0d) |
| Feb 22, 2022 | INCY | ↑ Buy | 525,804 | $67.96 | $35.7M | Indirect | Feb 22, 2022 (0d) |
| Feb 17, 2022 | KOD | ↑ Buy | 400,965 | $54.45 | $21.8M | Indirect | Feb 17, 2022 (0d) |
| Feb 14, 2022 | INCY | ↑ Buy | 1,598,374 | $66.91 | $107.0M | Indirect | Feb 14, 2022 (0d) |
| Jan 31, 2022 | KOD | ↑ Buy | 347,665 | $52.02 | $18.1M | Indirect | Jan 31, 2022 (0d) |
| Jan 25, 2022 | KOD | ↑ Buy | 501,111 | $57.49 | $28.8M | Indirect | Jan 25, 2022 (0d) |
| Dec 17, 2021 | INCY | ↑ Buy | 1,595,519 | $72.43 | $115.6M | Indirect | Dec 17, 2021 (0d) |
| Dec 1, 2021 | SGEN | ↓ Sell | 394,895 | $160.54 | $63.4M | Indirect | Dec 2, 2021 (1d) |
| Nov 18, 2021 | TLIS | ↑ Buy | 50,000 | $4.37 | $218K | Indirect | Nov 19, 2021 (1d) |
Each row is one filing's trades in one stock, summed. Shares and prices are as filed, before any later stock split.
Other MDGL insiders
Open-market trades in the last 12 months
About Baker Bros. Advisors (GP) LLC's insider trades
Baker Bros. Advisors (GP) LLC is an insider at Madrigal Pharmaceuticals (MDGL). Since May 9, 2013, it has reported 152 open-market purchases worth $5.34B and 57 sales worth $2.24B on SEC Form 4. In the last 12 months: 9 buys ($450.5M) and 2 sales ($318.0M).
Its filings also include grants and awards (260 filings), option exercises (43 filings), other transactions (37 filings), conversions (11 filings). These aren't open-market trades and aren't counted above.
How to read insider trades
Officers, directors and owners of more than 10% of a company must report trades in its stock on SEC Form 4, usually within two business days. Purchases with their own money are the stronger signal: insiders sell for many reasons (taxes, diversification, a house), but buy for one. See every MDGL insider trade, the latest insider trades across the market, or cluster buys, when several insiders buy the same stock within days.