5AM Opportunities I (GP), LLC
10% Owner
5AM Opportunities I (GP), LLC10% Owner
5AM Opportunities I (GP), LLC insider trades: Entrada Therapeutics (TRDA) stock buys and sales
10% Owner, Entrada Therapeutics Last trade Aug 7, 2026 43 Form 4 filings
$3.0M
Sold, last 12 months
3 sales
$0
Bought, last 12 months
0 buys
64
Open-market trades
since 2019
12
Companies
last trade 2026
Trades on the price chart
Daily close, with an arrow on each day they bought or sold
Companies
Where 5AM Opportunities I (GP), LLC reports to the SEC
TRDAEntrada Therapeutics
10% Owner · last filing Aug 10, 2026
-$4.1M
+$5.0M
ELVNEnliven Therapeutics
10% Owner · last filing Feb 16, 2024
-$29.8M
PEARPear Therapeutics
10% Owner · last filing Apr 12, 2023
-$5.7M
SCPHscPharmaceuticals
10% Owner · last filing Oct 11, 2022
-$4.9M
CINCCinCor Pharma
10% Owner · last filing Feb 28, 2023
+$25.5M
RLYBRallybio
10% Owner · last filing Jun 7, 2022
-$5.9M
+$8.0M
and 6 more companies
Open-market buys and sales
64 trades reported on SEC Form 4, newest first
| Date | Stock | Type | Shares | Price | Value | Holding | Reported |
|---|---|---|---|---|---|---|---|
| Aug 7, 2026 | TRDA | ↓ Sell | 62,811 | $6.88 | $432K | Direct | Aug 10, 2026 (3d) |
| Jul 31, 2026 | TRDA | ↓ Sell | 116,474 | $6.93 | $807K | Direct | Aug 3, 2026 (3d) |
| Nov 14, 2025 | TRDA | ↓ Sell | 200,000 | $8.80 | $1.8M | Direct | Nov 18, 2025 (4d) |
| Jul 9, 2025 | TRDA | ↓ Sell | 20,065 | $7.50 | $151K | Direct | Jul 11, 2025 (2d) |
| Jul 9, 2025 | TRDA | ↓ Sell | 6,935 | $7.50 | $52K | By 5AM Opportunities I, L.P. | Jul 11, 2025 (2d) |
| Jul 1, 2025 | TRDA | ↓ Sell | 92,891 | $6.93 | $644K | Direct | Jul 1, 2025 (0d) |
| Jul 1, 2025 | TRDA | ↓ Sell | 32,109 | $6.93 | $223K | By 5AM Opportunities I, L.P. | Jul 1, 2025 (0d) |
| Feb 14, 2024 | ELVN | ↓ Sell | 688,358 | $14.90 | $10.3M | By 5AMVentures VI, L.P. | Feb 16, 2024 (2d) |
| Feb 14, 2024 | ELVN | ↓ Sell | 136,642 | $14.90 | $2.0M | By 5AM Opportunities I, L.P. | Feb 16, 2024 (2d) |
| Jan 31, 2024 | ELVN | ↓ Sell | 417,187 | $15.00 | $6.3M | By 5AMVentures VI, L.P. | Feb 2, 2024 (2d) |
| Jan 31, 2024 | ELVN | ↓ Sell | 82,813 | $15.00 | $1.2M | By 5AM Opportunities I, L.P. | Feb 2, 2024 (2d) |
| Sep 26, 2023 | ELVN | ↓ Sell | 164,789 | $15.00 | $2.5M | By 5AM Ventures VI, L.P. | Sep 28, 2023 (2d) |
| Sep 26, 2023 | ELVN | ↓ Sell | 32,711 | $15.00 | $491K | By 5AM Opportunities I, L.P. | Sep 28, 2023 (2d) |
| Aug 24, 2023 | ELVN | ↓ Sell | 367,124 | $16.00 | $5.9M | By 5AM Ventures VI, L.P. | Aug 28, 2023 (4d) |
| Aug 24, 2023 | ELVN | ↓ Sell | 72,876 | $16.00 | $1.2M | By 5AM Opportunities I, L.P. | Aug 28, 2023 (4d) |
| Apr 10, 2023 | PEAR | ↓ Sell | 12,836,489 | $0.12 | $1.5M | By 5AM Ventures IV, L.P. | Apr 12, 2023 (2d) |
| Apr 10, 2023 | PEAR | ↓ Sell | 3,172,769 | $0.12 | $381K | By 5AM Opportunities I, L.P. | Apr 12, 2023 (2d) |
| Apr 10, 2023 | PEAR | ↓ Sell | 534,855 | $0.12 | $64K | By 5AM Co-Investors IV, L.P. | Apr 12, 2023 (2d) |
| Nov 15, 2022 | PEAR | ↓ Sell | 101,070 | $2.74 | $277K | By 5AM Ventures IV, L.P. | Nov 15, 2022 (0d) |
| Nov 15, 2022 | PEAR | ↓ Sell | 4,211 | $2.74 | $12K | By 5AM Co-Investors IV, L.P. | Nov 15, 2022 (0d) |
| Nov 2, 2022 | PEAR | ↓ Sell | 52,040 | $2.77 | $144K | By 5AM Ventures IV, L.P. | Nov 2, 2022 (0d) |
| Nov 2, 2022 | PEAR | ↓ Sell | 2,169 | $2.77 | $6K | By 5AM Co-Investors IV, L.P. | Nov 2, 2022 (0d) |
| Oct 10, 2022 | SCPH | ↓ Sell | 486,870 | $4.15 | $2.0M | By 5AM Ventures IV, L.P. | Oct 11, 2022 (1d) |
| Oct 10, 2022 | SCPH | ↓ Sell | 92,844 | $4.15 | $385K | By 5AM Opportunities I, L.P. | Oct 11, 2022 (1d) |
| Oct 10, 2022 | SCPH | ↓ Sell | 20,286 | $4.15 | $84K | By 5AM Co-Investors IV, L.P. | Oct 11, 2022 (1d) |
| Sep 16, 2022 | PEAR | ↓ Sell | 535,841 | $1.88 | $1.0M | By 5AM Ventures IV, L.P. | Sep 16, 2022 (0d) |
| Sep 16, 2022 | PEAR | ↓ Sell | 22,327 | $1.88 | $42K | By 5AM Co-Investors IV, L.P. | Sep 16, 2022 (0d) |
| Sep 8, 2022 | PEAR | ↓ Sell | 739,200 | $2.05 | $1.5M | By 5AM Ventures IV, L.P. | Sep 8, 2022 (0d) |
| Sep 8, 2022 | PEAR | ↓ Sell | 30,800 | $2.05 | $63K | By 5AM Co-Investors IV, L.P. | Sep 8, 2022 (0d) |
| Sep 7, 2022 | SCPH | ↓ Sell | 184,736 | $4.84 | $894K | By 5AM Ventures IV, L.P. | Sep 8, 2022 (1d) |
| Sep 7, 2022 | SCPH | ↓ Sell | 34,189 | $4.84 | $165K | By 5AM Opportunities I, L.P. | Sep 8, 2022 (1d) |
| Sep 7, 2022 | SCPH | ↓ Sell | 7,697 | $4.84 | $37K | By 5AM Co-Investors IV, L.P. | Sep 8, 2022 (1d) |
| Aug 18, 2022 | PEAR | ↓ Sell | 384,001 | $1.65 | $634K | By 5AM Ventures IV, L.P. | Aug 18, 2022 (0d) |
| Aug 18, 2022 | PEAR | ↓ Sell | 15,999 | $1.65 | $26K | By 5AM Co-Investors IV, L.P. | Aug 18, 2022 (0d) |
| Aug 15, 2022 | CINC | ↑ Buy | 487,333 | $30.00 | $14.6M | By 5AM Opportunities II, L.P. | Aug 17, 2022 (2d) |
| Aug 15, 2022 | CINC | ↑ Buy | 112,667 | $30.00 | $3.4M | By 5AM Ventures VI, L.P. | Aug 17, 2022 (2d) |
| Jun 3, 2022 | RLYB | ↓ Sell | 99,671 | $12.50 | $1.2M | By 5AM Ventures V, L.P. | Jun 7, 2022 (4d) |
| Jun 3, 2022 | RLYB | ↓ Sell | 50,329 | $12.50 | $629K | By 5AM Opportunities I, L.P. | Jun 7, 2022 (4d) |
| May 23, 2022 | RLYB | ↓ Sell | 66,447 | $13.00 | $864K | By 5AM Ventures V, L.P. | May 25, 2022 (2d) |
| May 23, 2022 | RLYB | ↓ Sell | 33,553 | $13.00 | $436K | By 5AM Opportunities I, L.P. | May 25, 2022 (2d) |
| Apr 11, 2022 | SCPH | ↓ Sell | 220,096 | $5.00 | $1.1M | By 5AM Ventures IV, L.P. | Apr 13, 2022 (2d) |
| Apr 11, 2022 | SCPH | ↓ Sell | 40,733 | $5.00 | $204K | By 5AM Opportunities I, L.P. | Apr 13, 2022 (2d) |
| Apr 11, 2022 | SCPH | ↓ Sell | 9,171 | $5.00 | $46K | By 5AM Co-Investors IV, L.P. | Apr 13, 2022 (2d) |
| Feb 8, 2022 | RLYB | ↓ Sell | 210,000 | $13.05 | $2.7M | Indirect | Feb 10, 2022 (2d) |
| Jan 11, 2022 | CINC | ↑ Buy | 312,500 | $16.00 | $5.0M | By 5AM Opportunities I, L.P. | Jan 13, 2022 (2d) |
| Jan 11, 2022 | CINC | ↑ Buy | 157,500 | $16.00 | $2.5M | By 5AM Ventures VI, L.P. | Jan 13, 2022 (2d) |
| Nov 16, 2021 | VOR | ↓ Sell | 330,706 | $15.30 | $5.1M | Indirect | Nov 18, 2021 (2d) |
| Nov 2, 2021 | TRDA | ↑ Buy | 250,000 | $20.00 | $5.0M | Indirect | Nov 4, 2021 (2d) |
| Nov 1, 2021 | CABA | ↓ Sell | 295,000 | $13.00 | $3.8M | Indirect | Nov 3, 2021 (2d) |
| Sep 7, 2021 | CABA | ↓ Sell | 625,000 | $9.70 | $6.1M | Indirect | Sep 9, 2021 (2d) |
Each row is one filing's trades in one stock, summed. Shares and prices are as filed, before any later stock split.
Other TRDA insiders
Open-market trades in the last 12 months
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About 5AM Opportunities I (GP), LLC's insider trades
5AM Opportunities I (GP), LLC is a 10% owner of Entrada Therapeutics (TRDA). Since Oct 7, 2019, it has reported 11 open-market purchases worth $72.1M and 53 sales worth $119.3M on SEC Form 4. In the last 12 months: 3 sales ($3.0M).
Its filings also include conversions (7 filings), other transactions (2 filings). These aren't open-market trades and aren't counted above.
How to read insider trades
Officers, directors and owners of more than 10% of a company must report trades in its stock on SEC Form 4, usually within two business days. Purchases with their own money are the stronger signal: insiders sell for many reasons (taxes, diversification, a house), but buy for one. See every TRDA insider trade, the latest insider trades across the market, or cluster buys, when several insiders buy the same stock within days.